guangdong plant chain science&technology development co.,ltd
Guangdong Zhilian Technology Development Co., Ltd.
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HD99 (Hexamidine Diisethionate) – Advanced Anti-Dandruff & Acne Treatment Active Ingredient
Product Overview
HD99 (INCI: Hexamidine Diisethionate) is a high-purity, water-soluble cationic compound with exceptional broad-spectrum antimicrobial properties. It effectively targets bacteria (Gram-positive and Gram-negative), fungi, yeasts, and molds—particularly *Pityrosporum ovale*, the primary microbe linked to dandruff and scalp irritation. Beyond its anti-dandruff efficacy, HD99 is a breakthrough ingredient for acne treatment, making it a versatile active for personal care formulations. Its mild yet potent action ensures excellent skin and scalp tolerance, even in sensitive areas like the eyes.
| Insp. Characteristic | data |
| appearance | white powder |
| solubility | Water soluble |
| active content | ≥99.0 |
| water | ≤0.5% |
Key Benefits
1, Powerful Antimicrobial Action:
Rapidly inhibits and kills dandruff-causing fungi and acne-triggering bacteria (Cutibacterium acnes).
Proven efficacy against scalp itching, flaking, and microbial imbalances.
2, Gentle & Non-Irritating:
Exceptionally tolerated by skin and scalp, with no ocular irritation—ideal for leave-on and rinse-off products.
3, Formulation-Friendly:
Water-soluble, eliminating the need for suspension agents (unlike ZPT).
Compatible with most cosmetic bases (shampoos, serums, creams) without affecting viscosity, pH, or clarity.
4, Synergistic & Stable:
Enhances performance when combined with other anti-dandruff agents (e.g., ZPT, OCT, climbazole).
Resists oxidation and maintains stability under varying temperatures and pH levels.
Applications & Recommended Dosage
1, Anti-Dandruff Hair Care
Shampoos & Scalp Treatments: Reduces flaking and itching by targeting P. ovale.
Dosage: 0.03–0.05% (standalone or combined with OCT/climbazole).
2, Acne & Oil-Control Products
Face Washes, Toners, Spot Treatments: Combats C. acnes and prevents breakouts.
Dosage: 0.1–0.2% .
3, Complementary Uses
Antimicrobial Deodorants: Controls odor-causing bacteria.
Intimate Hygiene Products: Gentle yet effective preservation.
Why Choose HD99?
Dual Action: Addresses both dandruff and acne with one ingredient.
Regulatory Edge: Safer alternative to restricted actives like ZPT (banned in EU for cosmetic use).
Ease of Use: No premixing or dispersion required—directly soluble in aqueous phases.
Packaging & Storage
1kg/bag
Store in a cool, dry place away from direct sunlight.
Safety & Compliance
Non-toxic, non-sensitizing, and suitable for sensitive skin.
Complies with global cosmetic regulations (EU, FDA, China).
Ideal for:
Dandruff-control shampoos
Anti-acne skincare lines
Preservative-free antimicrobial formulations
HD99 combines scientific efficacy with formulation flexibility, offering brands a future-proof solution for scalp and skin health. Contact us for technical support or samples!
